Pub. Date : 2021 Feb
PMID : 33278547
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Our results showed that the Curcumin binds p53Y220C with Kd = 3.169 +- 0.257 muM and it increases the DNA binding affinity of the mutant by 4-fold with Kd = 851.29 +- 186.27 nM. | Curcumin | tumor protein p53 | Homo sapiens |
| 2 | By caspase and Annexin V assays, we could demonstrate Curcumin at 3 muM to 8 muM concentration could initiate p53 mediated apoptosis in BxPC-3 cell lines. | Curcumin | tumor protein p53 | Homo sapiens |