Title : Exploring the molecular approach of COX and LOX in Alzheimer's and Parkinson's disorder.

Pub. Date : 2020 Dec

PMID : 33263931






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cytokines/chemokines excite phospholipase A2 and cyclooxygenases (COX), facilitating the release of arachidonic acid (AA) and docosahexaenoic acid (DHA) from membrane glycerophospholipids, in which the former is oxidized to produce pro-inflammatory eicosanoids (prostaglandins, leukotrienes and thromboxane"s), which intensify the neuroinflammatory events in the brain. Arachidonic Acid phospholipase A2 group IB Homo sapiens