Title : The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer.

Pub. Date : 2020 Dec

PMID : 33257855






1 Functional Relationships(s)
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1 Metabolomics and gene expression profiling pointed towards activation of the hexosamine biosynthesis pathway (HBP), another nitrogen-related metabolic pathway, in both mouse and human KRAS/LKB1 co-mutant tumours. Hexosamines KRAS proto-oncogene, GTPase Homo sapiens