Title : FGF23 contains two distinct high-affinity binding sites enabling bivalent interactions with α-Klotho.

Pub. Date : 2020 Dec 15

PMID : 33257569






1 Functional Relationships(s)
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Protein Name
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1 FGF23 stimulates the assembly of a signaling complex composed of alpha-Klotho (KLA) and FGF receptor (FGFR) resulting in kinase activation, regulation of phosphate homeostasis, and vitamin D levels. Phosphates klotho Homo sapiens