Title : Phosphatidylglycerol and surfactant: A potential treatment for COVID-19?

Pub. Date : 2020 Nov

PMID : 33254581






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In addition, a constituent of surfactant, phosphatidylglycerol, could mitigate COVID-19-induced lung pathology by: (3) decreasing excessive innate immune system stimulation via its inhibition of toll-like receptor-2 and -4 activation by microbial components and cellular proteins released by damaged cells, thereby limiting inflammation and the resultant pulmonary edema, and (4) possibly blocking spread of the viral infection to non-infected cells in the lung. Phosphatidylglycerols toll like receptor 2 Homo sapiens