Pub. Date : 2020 Nov 27
PMID : 33247192
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Weak acid-induced PGE2 production was significantly inhibited by cytosolic phospholipase A2 (cPLA2), ERK, and transient receptor potential cation channel subfamily V member 4 (TRPV4), a pH-sensing ion channel, inhibitors. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 2 | Weak acid-induced PGE2 production was significantly inhibited by cytosolic phospholipase A2 (cPLA2), ERK, and transient receptor potential cation channel subfamily V member 4 (TRPV4), a pH-sensing ion channel, inhibitors. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 3 | These results indicated that weak acids induce PGE2 production via TRPV4/ERK/cPLA2 in oesophageal epithelial cells, suggesting a role in GERD symptoms like heartburn. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |