Title : Diminution by captopril of the diuretic, natriuretic and kallikrein stimulating action of furosemide by reduction in its renal secretion.

Pub. Date : 1987

PMID : 3324714






4 Functional Relationships(s)
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1 Diminution by captopril of the diuretic, natriuretic and kallikrein stimulating action of furosemide by reduction in its renal secretion. Furosemide kallikrein related peptidase 4 Homo sapiens
2 After furosemide injection changes in plasma aldosterone concentration paralleled changes in renal kallikrein and kinin excretion. Furosemide kallikrein related peptidase 4 Homo sapiens
3 However, after captopril there was a sharp dissociation between aldosterone, which was diminished by captopril continuously, and renal kallikrein and kinins, which were still stimulated by furosemide. Furosemide kallikrein related peptidase 4 Homo sapiens
4 These results suggest that renal kallikrein-kinin system is stimulated by furosemide directly and independently of aldosterone secretion. Furosemide kallikrein related peptidase 4 Homo sapiens