Title : Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons.

Pub. Date : 2021 Feb 12

PMID : 33246331






1 Functional Relationships(s)
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1 Unexpectedly, phosphorylated tau was primarily accumulated in glutamic acid decarboxylase 67 (GAD67) GABAergic interneurons and, to a lesser extent, glutamate receptor 2/3-positive excitatory mossy cells, showing preferential extracellular vesicle-mediated GABAergic interneuronal tau propagation. Glutamic Acid microtubule associated protein tau Homo sapiens