Title : Analogues of 2'-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase.

Pub. Date : 2021 Dec

PMID : 33243025






4 Functional Relationships(s)
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1 Analogues of 2"-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase. 2'-hydroxychalcone acetylcholinesterase (Cartwright blood group) Homo sapiens
2 A series of C4-substituted tertiary nitrogen-bearing 2"-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. 2'-hydroxychalcone acetylcholinesterase (Cartwright blood group) Homo sapiens
3 Majority of the 2"-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinesterase (BuChE). 2'-hydroxychalcone acetylcholinesterase (Cartwright blood group) Homo sapiens
4 Majority of the 2"-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinesterase (BuChE). 2'-hydroxychalcone acetylcholinesterase (Cartwright blood group) Homo sapiens