Title : Furosemide as a Probe Molecule for the Treatment of Neuroinflammation in Alzheimer's Disease.

Pub. Date : 2020 Dec 16

PMID : 33225679






1 Functional Relationships(s)
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1 Our data demonstrate that furosemide inhibits the secretion of proinflammatory TNF-alpha, IL-6, and nitric oxide; downregulates the mRNA level of Cd86 and the protein expression of COX-2, iNOS; promotes phagocytic activity; and enhances the expression of anti-inflammatory IL-1RA and arginase. Furosemide tumor necrosis factor Homo sapiens