Title : Down-Regulation of Hypoxia-Inducible Factor-1α and Downstream Glucose Transporter Protein-1 Gene by β-elemene Enhancing the Radiosensitivity of Lung Adenocarcinoma Transplanted Tumor.

Pub. Date : 2020

PMID : 33223837






4 Functional Relationships(s)
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Protein Name
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1 The relationship between the radiosensitivity of beta-elemene and the expression of HIF-1alpha and GLUT-1 was analyzed. beta-elemene solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus
2 When beta-elemene was used in combination with radiation, the expression of HIF-1alpha and GLUT-1 was significantly decreased, and there was a positive correlation between the two genes. beta-elemene solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus
3 The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. beta-elemene solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus
4 The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. beta-elemene solute carrier family 2 (facilitated glucose transporter), member 1 Mus musculus