Pub. Date : 2020
PMID : 33223837
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Down-Regulation of Hypoxia-Inducible Factor-1alpha and Downstream Glucose Transporter Protein-1 Gene by beta-elemene Enhancing the Radiosensitivity of Lung Adenocarcinoma Transplanted Tumor. | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 2 | Purpose: To study the effect of beta-elemene on the radiosensitivity of A549 cell xenograft tumor and potential mechanisms by which beta-elemene regulates the expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and glucose transporter protein-1 (GLUT-1). | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 3 | The relationship between the radiosensitivity of beta-elemene and the expression of HIF-1alpha and GLUT-1 was analyzed. | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 4 | When beta-elemene was used in combination with radiation, the expression of HIF-1alpha and GLUT-1 was significantly decreased, and there was a positive correlation between the two genes. | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 5 | The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 6 | The underlying molecular mechanism is probably associated with the down-regulation of HIF-1alpha and GLUT-1 expression, suggesting that beta-elemene may directly or indirectly inhibit the expression of HIF-1alpha and GLUT-1. | beta-elemene | hypoxia inducible factor 1, alpha subunit | Mus musculus |