Title : Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics.

Pub. Date : 2021 Jan

PMID : 33221570






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, this occurs via the mitochondrial redistribution of uncoupled eNOS secondary to a PKC-dependent phosphorylation of eNOS at Threonine 495 (T495). Threonine nitric oxide synthase 3 Homo sapiens
2 Mechanistically, this occurs via the mitochondrial redistribution of uncoupled eNOS secondary to a PKC-dependent phosphorylation of eNOS at Threonine 495 (T495). Threonine nitric oxide synthase 3 Homo sapiens