Title : Esculetin protects human corneal epithelial cells from oxidative stress through Nrf-2 signaling pathway.

Pub. Date : 2021 Jan

PMID : 33220236






1 Functional Relationships(s)
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1 Our experimental results demonstrated that pretreatment with esculetin markedly increased the cell viability while decreased the apoptosis in H2O2-treated human corneal epithelial (HCE) cells, by regulating Bcl-2, Bax and caspase-3 protein expressions and by altering the imbalance of activities of intracellular reactive oxygen species (ROS) and superoxide dismutase (SOD). esculetin BCL2 apoptosis regulator Homo sapiens