Title : Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling.

Pub. Date : 2021 Jan

PMID : 33217171






1 Functional Relationships(s)
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1 The combined LNG-EE PBPK model was verified regarding CYP3A4-mediated interaction by comparing to published clinical DDI study data with carbamazepine, rifampicin, and efavirenz (CYP3A4 inducers). efavirenz cytochrome P450 family 3 subfamily A member 4 Homo sapiens