Title : Regulation of the protein glycosylation pathway in yeast: structural control of N-linked oligosaccharide elongation.

Pub. Date : 1987 Dec

PMID : 3321055






2 Functional Relationships(s)
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Protein Name
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1 The yeast Saccharomyces cerevisiae X2180 strain with the mnn1 mnn2 mnn9 mutations, all of which affect mannoprotein glycosylation, synthesizes N-linked oligosaccharides having the following structure: (Formula: see text) whereas the mnn1 mnn2 mutant extends the alpha 1----6-linked backbone of some of the core oligosaccharides by adding 20-30 mannose units. n-linked oligosaccharides alpha-1,3-mannosyltransferase MNN1 Saccharomyces cerevisiae S288C
2 The yeast Saccharomyces cerevisiae X2180 strain with the mnn1 mnn2 mnn9 mutations, all of which affect mannoprotein glycosylation, synthesizes N-linked oligosaccharides having the following structure: (Formula: see text) whereas the mnn1 mnn2 mutant extends the alpha 1----6-linked backbone of some of the core oligosaccharides by adding 20-30 mannose units. n-linked oligosaccharides alpha-1,3-mannosyltransferase MNN1 Saccharomyces cerevisiae S288C