Title : Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation.

Pub. Date : 2020 Nov

PMID : 33205006






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Genz-161 effectively inhibited GCS activity, and substantially suppressed the elevated Gb3 levels seen in GEMs of p53-mutant cells exposed to doxorubicin. Doxorubicin tumor protein p53 Homo sapiens