Title : Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation.

Pub. Date : 2020 Nov

PMID : 33205006






1 Functional Relationships(s)
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1 We report herewith that globotriaosylceramide (Gb3) is associated with cSrc kinase in GEMs and plays a crucial role in modulating expression of p53 R273H mutant and drug resistance. globotriaosylceramide alpha 1,4-galactosyltransferase (P blood group) Homo sapiens