Pub. Date : 2020 Nov 17
PMID : 33203750
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The loss of nqrA or nqrF led to the decrease of membrane potential, ATPase activity, and then ATP and cyclic AMP (cAMP), which reduced the cAMP/CRP (cAMP receptor protein) complex. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 2 | The loss of nqrA or nqrF led to the decrease of membrane potential, ATPase activity, and then ATP and cyclic AMP (cAMP), which reduced the cAMP/CRP (cAMP receptor protein) complex. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 3 | The loss of nqrA or nqrF led to the decrease of membrane potential, ATPase activity, and then ATP and cyclic AMP (cAMP), which reduced the cAMP/CRP (cAMP receptor protein) complex. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 4 | The loss of nqrA or nqrF led to the decrease of membrane potential, ATPase activity, and then ATP and cyclic AMP (cAMP), which reduced the cAMP/CRP (cAMP receptor protein) complex. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 5 | The reduced cAMP/CRP complex promoted l-alanine catabolism and inhibited l-alanine anabolism, causing reduced levels of alanine. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 6 | Our results suggest a novel mechanism by which the Na+-NQR system regulates antibiotic resistance via l-alanine metabolism in a cAMP/CRP complex-dependent manner.IMPORTANCE The Na+-NQR complex functions as a unique redox-driven sodium pump, generating membrane potential directly. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 7 | It proceeds by ATP and then cAMP/CRP regulon, which inhibits l-alanine catabolism and promotes l-alanine anabolism. | Cyclic AMP | C-reactive protein | Homo sapiens |
| 8 | These findings suggest a novel mechanism by which the Na+-NQR system regulates antibiotic resistance via l-alanine metabolism in a cAMP/CRP complex-dependent manner. | Cyclic AMP | C-reactive protein | Homo sapiens |