Title : Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors.

Pub. Date : 2021 Feb

PMID : 33203660






1 Functional Relationships(s)
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1 Saturation and kinetic binding studies with 2-[125I]-iodomelatonin revealed lead carbamates (carbaryl, fenobucarb, bendiocarb, carbofuran) to be orthosteric ligands with antagonist apparent efficacy at hMT1 and agonist apparent efficacy at hMT2 melatonin receptors. Carbaryl ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase Homo sapiens