Title : Mutations in the SARS-CoV-2 spike RBD are responsible for stronger ACE2 binding and poor anti-SARS-CoV mAbs cross-neutralization.

Pub. Date : 2020

PMID : 33200028






1 Functional Relationships(s)
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1 Here, we observed Val-to-Lys417 mutation in the receptor-binding domains (RBD) of SARS-CoV-2, which established a Lys-Asp electrostatic interaction enhancing its ACE2-binding. Lysine angiotensin converting enzyme 2 Homo sapiens