Title : Chinese herbal compounds against SARS-CoV-2: Puerarin and quercetin impair the binding of viral S-protein to ACE2 receptor.

Pub. Date : 2020

PMID : 33200026






3 Functional Relationships(s)
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Protein Name
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1 Chinese herbal compounds against SARS-CoV-2: puerarin and quercetin impair the binding of viral S-protein to ACE2 receptor. Quercetin angiotensin converting enzyme 2 Homo sapiens
2 Molecular docking analysis showed that puerarin and quercetin exhibit good binding affinity to ACE2, which was validated by surface plasmon resonance (SPR) assay. Quercetin angiotensin converting enzyme 2 Homo sapiens
3 Furthermore, SPR-based competition assay revealed that puerarin and quercetin could significantly affect the binding of viral S-protein to ACE2 receptor. Quercetin angiotensin converting enzyme 2 Homo sapiens