Title : Neuroprotective potential of the oxindole alkaloids isomitraphylline and mitraphylline in human neuroblastoma SH-SY5Y cells.

Pub. Date : 2020 Dec

PMID : 33194521






2 Functional Relationships(s)
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1 Thioflavin-T assay for assessing amyloid-beta (Abeta) aggregation of these alkaloids exhibited inhibitions at 60.321% +- 2.61 (50 muM) for isomitraphylline and 43.17% +- 3.48 (50 muM) for mitraphylline. Alkaloids amyloid beta precursor protein Homo sapiens
2 Thioflavin-T assay for assessing amyloid-beta (Abeta) aggregation of these alkaloids exhibited inhibitions at 60.321% +- 2.61 (50 muM) for isomitraphylline and 43.17% +- 3.48 (50 muM) for mitraphylline. Alkaloids amyloid beta precursor protein Homo sapiens