Pub. Date : 2020
PMID : 33192276
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |
| 2 | Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |
| 3 | Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |
| 4 | Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |
| 5 | These results indicate that BHBA regulates cellular signaling and multiple histone modifications to cooperatively modulate BDNF, suggesting a wide range of regulatory effects of BHBA in the central nervous system. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |
| 6 | These results indicate that BHBA regulates cellular signaling and multiple histone modifications to cooperatively modulate BDNF, suggesting a wide range of regulatory effects of BHBA in the central nervous system. | 3-Hydroxybutyric Acid | brain derived neurotrophic factor | Homo sapiens |