Pub. Date : 1987 Nov
PMID : 3319049
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present model of epinephrine containing and PNMT containing neurons in rat brain (and by extension other species) implies that epinephrine is primarily a postsynaptic metabolite of norepinephrine in forebrain due to the probable postsynaptic localization of PNMT. | Epinephrine | phenylethanolamine-N-methyltransferase | Rattus norvegicus |
| 2 | The present model of epinephrine containing and PNMT containing neurons in rat brain (and by extension other species) implies that epinephrine is primarily a postsynaptic metabolite of norepinephrine in forebrain due to the probable postsynaptic localization of PNMT. | Epinephrine | phenylethanolamine-N-methyltransferase | Rattus norvegicus |
| 3 | The balance of norepinephrine to epinephrine found in vesicles in these terminals would be a function of intraneuronal PNMT activity, MAO activity and reuptake which would be the major regulator of intraneuronal norepinephrine concentrations. | Epinephrine | phenylethanolamine-N-methyltransferase | Rattus norvegicus |
| 4 | Based on the distribution of PNMT and its association with major noradrenergic fiber tracts, epinephrine can be considered a site-selective metabolite of physiological and neuronal importance. | Epinephrine | phenylethanolamine-N-methyltransferase | Rattus norvegicus |