Title : Oxycodone attenuates vascular leak and lung inflammation in a clinically relevant two-hit rat model of acute lung injury.

Pub. Date : 2021 Feb

PMID : 33187816






1 Functional Relationships(s)
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1 Oxycodone upregulated the expression of claudin-5, ZO-1, AQP1, and AQP5 but downregulated the expression of TNF-alpha, IL-1beta, TLR4, NF-kappaB, MMP9, and caspase-3 and suppressed endothelial apoptosis in vivo and in vitro. Oxycodone interleukin 1 alpha Rattus norvegicus