Title : Role of the SIRT1/p53 regulatory axis in oxidative stress‑mediated granulosa cell apoptosis.

Pub. Date : 2021 Jan

PMID : 33179088






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1 The present study demonstrated that reactive oxygen species induced by H<sub>2</sub>O<sub>2</sub> resulted in human granulosa COV434 cell apoptosis via the regulation of sirtuin 1 (SIRT1)-mediated p53 activity. Reactive Oxygen Species tumor protein p53 Homo sapiens