Pub. Date : 2020
PMID : 33164545
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Eicosapentaenoic acid reduces inflammation and apoptosis by SREBP1/TLR4/MYD88. | Eicosapentaenoic Acid | sterol regulatory element binding transcription factor 1 | Mus musculus |
| 2 | In addition, overexpression of the sterol regulatory element-binding protein-1 (SREBP-1) reversed the protective effects of EPA in high glucose-treated podocytes. | Eicosapentaenoic Acid | sterol regulatory element binding transcription factor 1 | Mus musculus |
| 3 | In addition, overexpression of the sterol regulatory element-binding protein-1 (SREBP-1) reversed the protective effects of EPA in high glucose-treated podocytes. | Eicosapentaenoic Acid | sterol regulatory element binding transcription factor 1 | Mus musculus |
| 4 | EPA inhibits the SREBP-1/TLR4/MYD88 signaling in high glucose treated cells. | Eicosapentaenoic Acid | sterol regulatory element binding transcription factor 1 | Mus musculus |
| 5 | CONCLUSIONS: This study suggests that EPA protects against podocytes dysfunction by regulating SREBP-1 and these findings provide a better understanding for diabetic nephropathy and a novel therapeutic strategy (Fig. | Eicosapentaenoic Acid | sterol regulatory element binding transcription factor 1 | Mus musculus |