Title : Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups.

Pub. Date : 2020 Dec 21

PMID : 33156617






5 Functional Relationships(s)
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Protein Name
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1 Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups. Arsenic arsenite methyltransferase Homo sapiens
2 Predicted AS3MT Proteins Methylate Arsenic and Support Two Major Phylogenetic AS3MT Groups. Arsenic arsenite methyltransferase Homo sapiens
3 In this study, we evaluated whether 55 (out of which 47 were predicted based on protein sequence similarity) sequences encoding putative AS3MT orthologues in 47 species from different kingdoms can indeed methylate arsenic. Arsenic arsenite methyltransferase Homo sapiens
4 For example, the predicted AS3MT of the human gut bacterium Faecalibacterium prausnitzii methylated arsenic efficiently. Arsenic arsenite methyltransferase Homo sapiens
5 Further, it shows that humans carry two bacterial systems for arsenic methylation: one bacterium-derived AS3MT from Group 1 incorporated in the human genome and one from Group 2 in F. prausnitzii present in the gut microbiome. Arsenic arsenite methyltransferase Homo sapiens