Title : Effects of exercise modalities on BDNF and IL-1β content in circulating total extracellular vesicles and particles obtained from aged rats.

Pub. Date : 2020 Dec

PMID : 33148515






3 Functional Relationships(s)
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1 Taken that BDNF and anti-inflammatory effects have been related to functional outcomes, and BDNF and IL-1beta have been detected in circulating EVPs, our aim was to evaluate circulating total EVPs profile from adult and aged Wistar rats submitted to exercise modalities, namely aerobic, acrobatic, resistance or combined for 20 min, 3 times a week, during 12 weeks. evps brain-derived neurotrophic factor Rattus norvegicus
2 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps brain-derived neurotrophic factor Rattus norvegicus
3 A modality- and age-dependent effect on total EVPs cargo was observed; aerobic exercise induced an augment in BDNF and IL-1beta in EVPs from aged rats, while acrobatic and combined exercise modalities reduced IL-1beta content in EVPs from adult ones. evps brain-derived neurotrophic factor Rattus norvegicus