Pub. Date : 2020 Oct 28
PMID : 33145410
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. | Adenine | mutY DNA glycosylase | Homo sapiens |
| 2 | The human DNA base excision repair enzyme MUTYH (MutY homolog DNA glycosylase) excises undamaged adenine that has been misincorporated opposite the oxidatively damaged 8-oxoG, preventing transversion mutations and serving as an important defense against the deleterious effects of this damage. | Adenine | mutY DNA glycosylase | Homo sapiens |
| 3 | Herein, we synthesize and identify novel fluorescent adenine derivatives that can act as direct substrates for excision by MUTYH as well as bacterial MutY. | Adenine | mutY DNA glycosylase | Homo sapiens |