Title : Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1β and Interleukin-18 from Human Monocytes.

Pub. Date : 2020

PMID : 33144845






1 Functional Relationships(s)
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1 To address a potential heterogeneity in inflammasome functionality, ATP, chitosan, or silica oxide (SiO2) were used to induce NLRP3 inflammasome activation in THP-1 cells and the subsequent outcomes were quantified. Silicon Dioxide NLR family pyrin domain containing 3 Homo sapiens