Title : Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder.

Pub. Date : 2021 Feb

PMID : 33140216






1 Functional Relationships(s)
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1 Thus, we investigated the effect of fluvoxamine, a Sigma-1 receptor agonist, on Ito and ICa-L. Fluvoxamine enhanced Ito and altered its current kinetics, as shown by acceleration of activation and recovery from inactivation. Fluvoxamine sigma non-opioid intracellular receptor 1 Rattus norvegicus