Title : CD14 release induced by P2X7 receptor restricts inflammation and increases survival during sepsis.

Pub. Date : 2020 Nov 2

PMID : 33135636






1 Functional Relationships(s)
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1 Here we show for first time that P2X7 receptor induces the release of CD14 in extracellular vesicles, resulting in a net reduction in macrophage plasma membrane CD14 that functionally affects LPS, but not monophosphoryl lipid A, pro-inflammatory cytokine production. Lipid A CD14 antigen Mus musculus