Title : Adenosine A2B receptor: A pathogenic factor and a therapeutic target for sensorineural hearing loss.

Pub. Date : 2020 Dec

PMID : 33131093






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ada-/- mice cochlea with elevated adenosine caused substantial nerve fiber demyelination and mild hair cell loss. Adenosine adenosine deaminase Mus musculus
2 ADA enzyme therapy in these mice normalized cochlear adenosine levels, attenuated SNHL, and prevented demyelination. Adenosine adenosine deaminase Mus musculus