Title : Effectiveness and safety of high dose clopidogrel plus aspirin in ischemic stroke patients with the single CYP2C19 loss-of-function allele: a randomized trial.

Pub. Date : 2020 Oct 29

PMID : 33121452






3 Functional Relationships(s)
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1 Effectiveness and safety of high dose clopidogrel plus aspirin in ischemic stroke patients with the single CYP2C19 loss-of-function allele: a randomized trial. Aspirin cytochrome P450 family 2 subfamily C member 19 Homo sapiens
2 CONCLUSIONS: In patients with ischaemic stroke who had a single CYP2C19 loss-of-function allele and moderate to severe cerebral stenosis, fewer vascular events occurred within 3 months with high dose of clopidogrel and aspirin than with normal dose of clopidogrel and aspirin. Aspirin cytochrome P450 family 2 subfamily C member 19 Homo sapiens
3 CONCLUSIONS: In patients with ischaemic stroke who had a single CYP2C19 loss-of-function allele and moderate to severe cerebral stenosis, fewer vascular events occurred within 3 months with high dose of clopidogrel and aspirin than with normal dose of clopidogrel and aspirin. Aspirin cytochrome P450 family 2 subfamily C member 19 Homo sapiens