Title : Cholesterol Crystals and NLRP3 Mediated Inflammation in the Uterine Wall Decidua in Normal and Preeclamptic Pregnancies.

Pub. Date : 2020

PMID : 33117348






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cholesterol crystal mediated NLRP3 inflammasome activation is central to cardiovascular disease and the pathway has been implicated in placental inflammation in preeclampsia. Cholesterol NLR family pyrin domain containing 3 Homo sapiens
2 Our findings suggest that decidual accumulation of cholesterol crystals may activate the NLRP3 inflammasome and contribute to decidual inflammation and that this pathway is strengthened in areas with close maternal-fetal interaction in preeclampsia without FGR. Cholesterol NLR family pyrin domain containing 3 Homo sapiens