Title : Involvement of nicotinic acetylcholine receptors in behavioral abnormalities and psychological dependence in schizophrenia-like model mice.

Pub. Date : 2020 Dec

PMID : 33109433






3 Functional Relationships(s)
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1 These effects of (-)-NIC were completely blocked by both methyllycaconitine, a selective alpha7 nAChR antagonist, and dihydro-beta-erythroidine (DHbetaE), a selective alpha4beta2 nAChR antagonist. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 These effects of (-)-NIC were completely blocked by both methyllycaconitine, a selective alpha7 nAChR antagonist, and dihydro-beta-erythroidine (DHbetaE), a selective alpha4beta2 nAChR antagonist. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 These findings suggest that alpha7 nAChR is associated with development of disease and is implicated in the therapeutic effect of nicotine in SCZ. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus