Title : Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice.

Pub. Date : 2020 Dec

PMID : 33105029






3 Functional Relationships(s)
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Protein Name
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1 In adult rodents, inhibition of Cyp26a1 and Cyp26b1 increases atRA concentrations and signaling. Tretinoin cytochrome P450, family 26, subfamily b, polypeptide 1 Mus musculus
2 Postnatal knockout of Cyp26b1 resulted in increased atRA concentrations in the skin while the postnatal knockout of both Cyp26a1 and Cyp26b1 resulted in increased atRA concentrations in the liver, serum, skin, spleen, and intestines. Tretinoin cytochrome P450, family 26, subfamily b, polypeptide 1 Mus musculus
3 Postnatal knockout of Cyp26b1 resulted in increased atRA concentrations in the skin while the postnatal knockout of both Cyp26a1 and Cyp26b1 resulted in increased atRA concentrations in the liver, serum, skin, spleen, and intestines. Tretinoin cytochrome P450, family 26, subfamily b, polypeptide 1 Mus musculus