Title : Reactive Oxygen Species Induce Endothelial Differentiation of Liver Cancer Stem-Like Sphere Cells through the Activation of Akt/IKK Signaling Pathway.

Pub. Date : 2020

PMID : 33101583






2 Functional Relationships(s)
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1 We also found that hydrogen peroxide or BSO induces the phosphorylation of Akt and IKK of endothelial differentiated sphere cells. Hydrogen Peroxide AKT serine/threonine kinase 1 Homo sapiens
2 Accordingly, both Akt1/2 kinase inhibitor and BAY 11-7082 inhibited hydrogen peroxide and BSO-mediated endothelial differentiation of cancer stem-like sphere cells. Hydrogen Peroxide AKT serine/threonine kinase 1 Homo sapiens