Title : Inhibitory effects of interleukin 1 on insulin secretion, insulin biosynthesis, and oxidative metabolism of isolated rat pancreatic islets.

Pub. Date : 1987 Oct

PMID : 3308437






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IL-1 was found to reduce insulin release in culture and totally inhibit glucose-stimulated insulin release in short-term incubations. Glucose interleukin 1 alpha Homo sapiens
2 Islet (pro)insulin biosynthesis, glucose oxidation, and oxygen uptake at 16.7 mM glucose were partially inhibited by IL-1. Glucose interleukin 1 alpha Homo sapiens