Title : Tumor-associated macrophages promote human hepatoma Huh-7 cell migration and invasion through the Gli2/IGF-II/ERK1/2 axis by secreting TGF-β1.

Pub. Date : 2020 Nov 1

PMID : 33081566






2 Functional Relationships(s)
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1 AIM: In this study, we explored the ability of TAMs to affect the malignant phenotype of human hepatoma Huh-7 cells through the Gli2/IGF-II/ERK1/2 pathway. Tamoxifen mitogen-activated protein kinase 3 Homo sapiens
2 CONCLUSION: The TGF-beta1 secreted by TAMs promotes the migration, invasion and EMT of human hepatoma Huh-7 cells through the Gli2/IGF-II/ERK1/2 pathway. Tamoxifen mitogen-activated protein kinase 3 Homo sapiens