Title : The insulin-receptor interaction: is the kinetic approach for inferring negative-cooperative site-site interactions valid?

Pub. Date : 1987 Aug 31

PMID : 3307777






2 Functional Relationships(s)
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1 However, when insulin binding to purified liver plasma membranes was measured at 15 degrees C in 50 mM Tris, pH 7.5 containing 0.1% bovine serum albumin and 100 U/ml bacitracin, the insulin binding data was characterised by a linear Scatchard plot and a Hill plot with a slope equal to unity. Tromethamine insulin Homo sapiens
2 However, when insulin binding to purified liver plasma membranes was measured at 15 degrees C in 50 mM Tris, pH 7.5 containing 0.1% bovine serum albumin and 100 U/ml bacitracin, the insulin binding data was characterised by a linear Scatchard plot and a Hill plot with a slope equal to unity. Tromethamine insulin Homo sapiens