Title : Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy.

Pub. Date : 2020 Dec

PMID : 33051362






1 Functional Relationships(s)
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1 Tricyclic chromenone-based inhibitors B-I09 and D-F07, prodrugs harboring the aldehyde-masking group, emerged as the most reliable inhibitors for potent suppression of XBP-1s expression in MM cells. coumarin X-box binding protein 1 Homo sapiens