Title : Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis.

Pub. Date : 2020 Nov 18

PMID : 33051352






1 Functional Relationships(s)
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1 Similar to ALS patients, a compensatory down regulation of cholesterol synthesis occurred in the SC of SOD1G93A mice; levels of sterol regulatory element binding protein 2 (SREBP2) - a transcriptional regulator of cholesterol synthesis, progressively declined. Cholesterol superoxide dismutase 1 Homo sapiens