Title : LPA3-mediated lysophosphatidic acid signaling promotes postnatal heart regeneration in mice.

Pub. Date : 2020

PMID : 33042260






1 Functional Relationships(s)
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1 Genome-wide transcriptional profiling and additional mechanistic studies showed that LPA induces cardiomyocyte proliferation through the PI3K/AKT, BMP-Smad1/5, Hippo/YAP and MAPK/ERK pathways in vitro, whereas only ERK was confirmed to be activated by LPA-LPA3 signaling in vivo. lysophosphatidic acid thymoma viral proto-oncogene 1 Mus musculus