Title : The effect of genetic variations for interleukin-10 (IL-10) on the efficacy of immunosuppressive therapy in patients after kidney transplantation.

Pub. Date : 2020 Dec

PMID : 33039969






6 Functional Relationships(s)
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1 The aim of the study was to examine the correlation between tacrolimus (TAC) dose and genetic variation for interleukin-10 (IL-10) and its effect on the therapeutic outcome. Tacrolimus interleukin 10 Homo sapiens
2 The aim of the study was to examine the correlation between tacrolimus (TAC) dose and genetic variation for interleukin-10 (IL-10) and its effect on the therapeutic outcome. Tacrolimus interleukin 10 Homo sapiens
3 The aim of the study was to examine the correlation between tacrolimus (TAC) dose and genetic variation for interleukin-10 (IL-10) and its effect on the therapeutic outcome. Tacrolimus interleukin 10 Homo sapiens
4 The aim of the study was to examine the correlation between tacrolimus (TAC) dose and genetic variation for interleukin-10 (IL-10) and its effect on the therapeutic outcome. Tacrolimus interleukin 10 Homo sapiens
5 The analysis of the correlation between TAC dose and IL-10 genetic variation for the -1082A > G polymorphism revealed that patients with the AA genotype required lower immunosuppressive drug doses (AA: 3.54 +- 2.38 mg/day vs AG: 6.18 +- 5.10 mg/day, GG: 4.44 +- 3.01 mg/day). Tacrolimus interleukin 10 Homo sapiens
6 The results of the study indicated that the IL-10 -1082A > G polymorphism may in fact influence the TAC dose. Tacrolimus interleukin 10 Homo sapiens