Title : Loss of tumor intrinsic PD-L1 confers resistance to drug-induced apoptosis in human colon cancer.

Pub. Date : 2021 Jan

PMID : 33030957






1 Functional Relationships(s)
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1 Inhibition of MEK/ERK by cobimetinib or CDK inhibitor dinaciclib was shown to attenuate mutant BRAF-induced PD-L1 coincident with reduced c-JUN and YAP expression whose combined knockdown reduced PD-L1. dinaciclib B-Raf proto-oncogene, serine/threonine kinase Homo sapiens