Title : Multi-target approach for Alzheimer's disease treatment: computational biomolecular modeling of cholinesterase enzymes with a novel 4-N-phenylaminoquinoline derivative reveal promising potentials.

Pub. Date : 2021 Jul

PMID : 33030113






1 Functional Relationships(s)
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1 More recently, a novel series of 4-N-phenylaminoquinolines was synthesized and evaluated against AChE and BuChE in which one of the compounds displayed appreciable inhibition compared to the standard compound, galantamine. Galantamine acetylcholinesterase (Cartwright blood group) Homo sapiens