Title : S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.

Pub. Date : 2020 Oct 7

PMID : 33027770






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SAC increased the nuclear translocation of Nrf2 and activated the Nrf2/HO1 signaling pathway in TBHP-treated chondrocytes. tert-Butylhydroperoxide heme oxygenase 1 Mus musculus
2 Collectively, these findings show that SAC ameliorates OA pathology in TBHP-treated chondrocytes and DMM model mice by activating the Nrf2/HO1 signaling pathway. tert-Butylhydroperoxide heme oxygenase 1 Mus musculus